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Beilstein J. Org. Chem. 2013, 9, 2762–2766, doi:10.3762/bjoc.9.310
Graphical Abstract
Figure 1: Structures of resolvins D1 (1) and D2 (2).
Scheme 1: Retrosynthetic analysis of RvD2 (1).
Scheme 2: Synthesis of aldehyde 7 and phosphonium salt 6.
Scheme 3: Synthesis of vinyl iodide 4.
Scheme 4: Synthesis of enyne 3.
Scheme 5: Completion of the synthesis of RvD2 (1).